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I don't know Reaper. I always found it hostile and confusing, and it's not free software, so it's never been an option for me.

LMMS has major shortcomings for me, and I find it confusing for mixing and sending signals.
It has a strong point, very flexible automations, but it doesn't make up for it (it's a feature I use sporadically and only in some projects).

Ardour isn't confusing, but it is cumbersome, it makes easy things difficult and it has limitations in midi.

Qtractor fits perfectly with my way of thinking, feeling and creating.

So I don't know what you mean by master and slave groups.
If you describe what you want to do, I could try to help you on how to do it in Qtractor.