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Thanks once again for looking into all this :-) I've tested 0.5.8.15 and here's where we stand:

7) CHANGING SOFT SYNTH PATCH CAUSES DEDICATED AUDIO CONNECTIONS TO BE LOST
Appears to be fine now, provided that you've saved the project before changing the patch. If you take a completely new project and proceed as per the original bug, the issue will still occur. However, I don't think this is a problem, as if you're going to be doing any non-standard routing, you will have saved the project first.

3) DEDICATED AUDIO CONNECTIONS NOT PERSISTENT
This also looks fixed now.

1) SOFT SYNTH GUI PATCH CHANGE NOT DETECTED
As per comment on the ticket.

INSERTS - CONNECTIONS WINDOW UN-SELECTABLE
I think you're probably still looking into this so haven't made any changes, but just FYI, the Connections tab is still un-selectable after clicking Sends/Returns on the Insert window.

Thanks again!