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I tried on 2 different machines with very different HW on them, cheap Intel CPU vs expensive Intel CPU, Intel GPU vs Nvidia with proprietary drivers, no difference. The problem seems to be the presence of "curved" connections, like when you have more output connections coming back to inputs in the same client, like Ardour. When you have "straight" connections there is no noticeable lag, like you could have with a simple Carla setup, Ex: Synth > FX > Mixer > System Out.