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yes, it could but it can be even worse than that: the JACK/ALSA configuration might be just far from ideal when regarding the hardware device at hand: TL;DR: you may have it wrong or bad configured...

what are you using to setup JACK? is it cadence? is it qjackctl? which JACK version? yes, there are too many ways and variables that might go wrong in there and only one another that yet goes just right...

seeya