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- mute a clip?
see Region gain/clip gain and input trim, on setting gain=-70dB (audio) or volume=0% (midi).

- mute a note?
you don't just mute a note. you may set it's velocity to a minimum value (which is 1; velocity=0 is usually synonymous to a note-off event) and that might do what you want, however it depends on the target instrument or sound generator to comply with that. anyway, if you don't want the note to be heard, don't put it there. simple as that.

byee