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I think there are 2 questions you should care about:
1. Do you prefer a special distribution. Maybe if you come from Windows, SUSE would be a good proposal.
2. Do you need Realtime-Kernel?

I would suggest you, to use an audio distribution, because the tools and codecs will already be pre-selected in this distributions, along with a realtime kernel. Jacklab would be a distribution which uses SUSE 10.2. I would prefer Ubuntu-Studio because I like the apt-get package mechanism and the gnome GUI. But there are some more Audio-distributions like: 64studio, ...

The easiest way might be: Install Ubuntu-Studio from DVD, Install qtraktor package with package manager and have fun...